Overview The use of psychedelics has been historically highly stigmatised due to unfounded claims as to their harmfulness. These claims were often made from a politically motivated perspective and not subject to rigorous scientific enquiry. In the years since, evaluations of various substances, legal and non, and their impact on the individual and society has shown that classic psychedelic substances and cannabis not only have low levels of harm, but in some cases the risks are negligible. By comparison, commonly used substances such as alcohol, tobacco, heroin, cocaine amphetamines, painkillers such as fentanyl and oxycontin, pose major risks to individual health and public safety. Not only can we use this to demonstrate the fallacy behind the demonisation of psychedelics compared to other substances, but also an irony emerges where psychedelic and entheogenic substances are seeing more and more positive clinical results in improving conditions in participants who often turn to…...